Pharmaceutical Containment Technologies achieved the stringent containment criteria required for a high-level research university: reaching an OEL of <.1 ug/m3 when handling kilograms of API.

The institution - handling API and similar compounds in the production and formulation processes - sought to optimize containment utilizing limited HVAC capacity. The solution (derived from concept designs, enclosure mock-ups, SOP development and site acceptance testing) included implementing PCT's custom enclosure design which allowed for interchangeable equipment (friabilators, comills, tablet presses, sieve-shakers and granulators)  be used under containment as well as utilizing a plug'n'play layout to accommodate each application.

By achieving the OEL <.1 ug/m3, health and safety requirement can be achieved in the laboratory without restrictive and excessive protective equipment.

Proven Nano-Particle Containment

PCT’s powder-handling enclosure provides proven nano-particle containment with exposure <2000 np/ cm3 when pouring 100g of nanoalumina.

Testing performed by UMass Lowell’s Center for High- rate Nano-Manufacturing found PCT’s enclosure to “be very effective at containing nanoalumina during pouring and transfer.”

PCT provides standard and custom containment systems for the handling of potent compounds, API’s, nano-particles and other hazards.
 

Applications include:

• formulation  
• characterization  
• robotics  
• aerosolization  
• fume scavenging  
• weighing  
• milling/grinding  
• compound extruder 
• dispensing

Download the Nano-particle Containment PDF